</> CENTRE FOR INFORMATICS AND COMPUTING
@ RUĐER BOŠKOVIĆ INSTITUTE </>
Driving Scientific Innovation through HPC and Next-Gen Computing
We do research, science support and knowledge sharing
The Centre for Informatics and Computing (CIR) is a research unit of the Ruđer Bošković Institute (IRB) dedicated to providing scientific support to researchers and the business sector, as well as advancing research in High-Performance Computing (HPC) and parallel and distributed computing.
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Research & Innovation
CIR drives research and innovation in HPC and are specialized in developing and optimizing scientific applications for clusters and supercomputers—powering breakthroughs in science, medicine, and technology.
OUR ACTIVE PROJECTS
DAP aims to create a democratic, trustworthy and efficient game-changing infrastructure for academic publishing
DNMT - 1
Uncovering new DNA methylation inhibitors through the advanced power of supercomputing technology
PARADIS
Efficient parallelization and optimization of algorithms for future heterogeneous and distributed systems
EBSI-NE
Development and adoption of the EBSI network at the European level by increasing the number of validator nodes in the production network
EURO HPC
Establishment of a network of National Centers of Competence (NCC) in the most efficient way.
PUBLISHED PAPERS
Published: 11 November 2025
Making Big, Messy Data Behave - with the Help of HPC
Our researchers Nenad Mijić, Abhiram Kaushik, Dario Zivkovic and Davor Davidovic have developed a new way to handle one of the trickiest problems in scientific computing: working with huge, unstable datasets that normally break traditional math methods.
Published: 13 August 2025
From Idea to Drug Candidate: What Happens When Chemistry and HPC Work Together
In the latest research published in Journal of Molecular Structure, we used molecular docking and molecular dynamics simulations (powered by HPC infrastructure) to predict binding to the BRAFV600E protein, conducted biological assays to test anti-proliferative activity across multiple cancer cell lines and evaluated kinase inhibition performance against BRAFV600E.
Published: 25 October 2025
Targeting BRAFV600E with the Power of HPC
The BRAFV600E mutation plays a key role in several cancers, including melanoma, thyroid, and colorectal cancer.
In the latest paper that was co-authored by Jurica Novak, that's titled: "Pyrimidin-4-bromobenzenesulfonamide/-4-nitrobenzenesulfonamide hybrids as potential BRAFV600E inhibitors: experimental, computational and biological evaluations" a new series of pyrimidine–sulfonamide hybrid molecules where design inspired by existing BRAF inhibitors and with the use of HPC power.
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Science
support
The Center for Informatics and Computing (CIR) is committed to empowering researchers and the business sector with cutting-edge scientific support through HPC technologies.
By leveraging advanced computational tools and expertise, CIR helps drive innovation, accelerate discoveries, and solve complex challenges across a wide range of industries.
HIGHLIGHTS
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ADVANCING SCIENCE
Projects, papers, seminars, and conferences form the backbone of our extensive network of connections. Our global collaborations not only give us a competitive edge in future endeavors but also provide deep insights into cutting-edge developments. These partnerships enhance our expertise and expand the horizons of our knowledge.